Bruno Fernandes scored his first goal for Manchester United and set up goals for Anthony Martial and Mason Greenwood as the Reds beat Watford 3-0 at Old Trafford.
Goals by Rodri and Kevin De Bruyne sealed an easy victory for Manchester City over West Ham following their winter break.
Manchester United could not break down a stubborn Wolves side who earned a point despite the best efforts of new Reds signing Bruno Fernandes.
Nervous Manchester City qualified for the final of the Carabao Cup despite a 1-0 defeat to a Manchester United side who finished with 10-men in a tense encounter.
Fulham lost their captain Tim Ream to a red card after 6 minutes, conceded a penalty, and handed the FA Cup tie to Manchester City in the second half after gifting Gabriel Jesus two goals.