Edinson Cavani scored an injury time winner as Manchester United battled back to beat Southampton at St Mary’s.
Riyad Mahrez hit a hat trick and Benjamin Mendy and Ferran Torres also scored as Manchester City thrashed Burnley 5-0 at the Etihad again.
Bruno Fernandes’ twice taken penalty earned Manchester United a belated first home Premier League win of the season against West Brom.
Tottenham beat Manchester City at White Hart Lane with goals by Son Heung-min and Giovani Lo Celso to go top of the Premier League overnight for the first time since August 2014.
Seven games into the Premier League campaign and Manchester City, remarkably, remain in the bottom half of the table following their failure to beat Liverpool.